Bills Favored to Edge Vikings in Clash of 6-1 Teams

The matchup pits the NFL’s top-scoring offense against its toughest defense. Buffalo is averaging 33.3 points per game, while Minnesota has allowed just 13.3, setting up a test of whether the Bills can keep producing against the league’s stingiest unit.

Pro Picks expects Buffalo to win 23-17, even without needing to reach its usual scoring pace. The Vikings’ offense has struggled, ranking 29th in yards per game at 279.4 and 27th in scoring at 20 points per game.

Minnesota could get a boost if Carson Wentz plays in place of Kyler Murray, who is dealing with a hamstring issue. The Bills are favored by 3½ points on the road.